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lab profile


Aziz Aboobaker

University of Nottingham
Department of Genetics and Genomics
Nottingham, Nottinghamshire NG3 4JT
United Kingdom


Taxa Studied: Invertebrate Animals
Techniques Employed: Degenerate PCR, Quantitative PCR (qPCR), Sanger Sequencing, 454 Pyrosequencing, Solexa (Illumina) Sequencing, SOLiD Sequencing, Bioinformatics/Sequence Analysis, In Situ Hybridization, Antibody Staining, RNA interference(RNAi), Sectioning for Histology, Epifluoresence Microscopy, Confocal Microscopy, Time-Lapse Microscopy, Transgenesis, Morpholinos, Other, Fluoresecence assisted cell sorting, microinjection techniques for various applications
Research Description: We are broadly interested in understanding the morphological diversity observed in extant animal taxa. What are the major network level changes in genetic networks that account for the differences in developmental and life history trajectories in animals. What are they underlying evolutionary mechanisms that contribute to this? What is the order and importance of these? Most of the researchers in the lab currently work with planarian flatworms and study regeneration and stem cell bioology in this fascinating system. We believe that it will be broadly informative about regenerative mechanisms and provide novel ideas and molecular clues towards a better basic understanding of how we might one day use regeneration in a medical context. We also have projects using other invertebrate animal systems including the crustacean Parhayle hawaiienesis and the tardigrade Hypsibius dujardini.
Lab Web Page: http://www.aboobakerlab.com
Willing to Host Undergraduates: YES
Actively Seeking Undergraduates: YES
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