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lab profile
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Daniel Meulemans Medeiros University of Colorado, Boulder
CU Boulder, EBIO Department Ramaley N122 MC334
Boulder, CO 80309
USA
Daniel.Medeiros@Colorado.edu
303 492 6180
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| PI: |
YES |
| Taxa Studied: |
Invertebrate Animals, Vertebrate Animals |
| Techniques Employed: |
Degenerate PCR, Bioinformatics/Sequence Analysis, In Situ Hybridization, Epifluoresence Microscopy, Transgenesis, Morpholinos, Mutagenesis |
| Research Description: |
In my lab, we are interested in understanding the evolution of our own subphylum, the vertebrates. To do this, we study developmental gene expression, regulation, and function in three model organisms; lamprey, amphioxus, and zebrafish. Lamprey, a jawless vertebrate, is the most basal vertebrate amenable to experimental manipulation at embryonic stages. Amphioxus is the most basal extant chordate and is thought to closely resemble the invertebrate ancestor of the vertebrates. Zebrafish, a teleost, is one of the most experimentally tractable vertebrate model systems. By comparing lamprey and amphioxus development with that of zebrafish, and other vertebrates like frog and salamander, we aim to reconstruct the genetic and developmental changes underlying the earliest events in vertebrate evolution. |
| Lab Web Page: |
http://www.colorado.edu/eeb/facultysites/medeiros/Home.html |
| Willing to Host Undergraduates: |
YES |
| Actively Seeking Undergraduates: |
YES |
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