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lab profile
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Ian Dworkin Michigan State University
Dept. of Zoology,
203 Natural Sciences Bldg.
East Lansing, MI 48824
US
idworkin@msu.edu
5174326733
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| PI: |
YES |
| Taxa Studied: |
Plants, Invertebrate Animals |
| Techniques Employed: |
Quantitative PCR (qPCR), Microarrays, Solexa (Illumina) Sequencing, Bioinformatics/Sequence Analysis, QTL Mapping, SNP Mapping, Antibody Staining, Transgenesis, Other, RNA interference(RNAi), Introgression of alleles into multiple genetic backgrounds |
| Research Description: |
Our research focuses on using genetic and genomic approaches to address outstanding questions in the evolution of complex phenotypes. We primarily use Drosophila (among other systems) as a model system to examine the interplay of standing genetic variation and environmental heterogeneity and their contribution to trait expression and variation; and how this interaction is itself shaped by evolutionary forces such as natural selection and drift. While some research programs focus on either the genetics of trait expression, traditionally using mutations (or other perturbations) of large effect, or on genetic variation within populations, utilizing natural variation (usually with much more subtle phenotypic effects), we successfully integrate both of these approaches along with genomic methods (transcriptional profiling, genome wide mapping) into our work to answer our questions. |
| Lab Web Page: |
http://https://www.msu.edu/~idworkin/ |
| Willing to Host Undergraduates: |
YES |
| Actively Seeking Undergraduates: |
YES |
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