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lab profile
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Klaus Brehm University of Wuerzburg
Josef-Schneider-Strasse 2
Wuerzburg, Bavaria D-97080
Germany
kbrehm@hygiene.uni-wuerzburg.de
+49 931-201-47251
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| PI: |
YES |
| Taxa Studied: |
Invertebrate Animals |
| Techniques Employed: |
Degenerate PCR, Quantitative PCR (qPCR), Sanger Sequencing, 454 Pyrosequencing, Bioinformatics/Sequence Analysis, Antibody Staining, Sectioning for Histology, Sectioning for Electron Microscopy, Transgenesis, RNA interference(RNAi) |
| Research Description: |
We are studying molecular host-parasite interaction mechanisms in cestode infections. Our model system is the fox-tapeworm Echinococcus multilocularis. We have established in vitro cultivation methods for the Echinococcus larval stage and for the parasite's totipotent stem cells. We're doing genetics, genomics, transcriptomics and proteomics on cestode larvae. We particularly study parasite signal transduction mechanisms and are developing novel drugs against the parasite larvae. We're also interested in parasite evolution and development. |
| Lab Web Page: |
http://www.hygiene.uni-wuerzburg.de/forschung/ag_brehm/ |
| Willing to Host Undergraduates: |
YES |
| Actively Seeking Undergraduates: |
YES |
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