Applying for Funding
Symposia and Workshops
Finding a Lab
Join the EDEN Network
Participating Labs
Research Exchange Experiences
Steering Committee
Extavour Lab
lab profile


Linda Holland

University of California San Diego
9500 Gilman Drive -0202
La Jolla, California 92093


Taxa Studied: Invertebrate Animals, amphioxus, cephalochordates
Techniques Employed: Degenerate PCR, Solexa (Illumina) Sequencing, SOLiD Sequencing, In Situ Hybridization, Antibody Staining, Sectioning for Histology, Sectioning for Electron Microscopy, Epifluoresence Microscopy, Transgenesis, Morpholinos, evolution of development, developmental mechanisms, chordate evolution
Research Description: I pioneered evo-devo research on amphioxus. Our overall question is how the vertebrates evolved from their invertebrate ancestors. To that end, we use amphioxus as a proxy for the common ancestor of amphioxus and the vertebrates. At present we are studying two species, Branchiostoma floridae and Asymmetron lucayanum. We are breeding both species out of season in the laboratory. I am focusing on evolution of the nervous system and early development including left/right asymmetry as well as alternative splicing. We are doing transcriptomics and sequencing the Asymmetron genome.
Lab Web Page:
Willing to Host Undergraduates: YES
Actively Seeking Undergraduates: NO
Copyright © 2010 EDEN Evo-Devo-Eco Network. All Rights Reserved. Site designed by Academic Web Pages.
EDEN Logo: Daniel Christianson. Logo Image: Frederike Alwes.