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lab profile
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Stefano Tiozzo Observatoire Oceanologique de Villefranche sur Mer Quai de la Darse
Villefranche-sur-Mer, Cote D 6234
France
tiozzo@obs-vlfr.fr +33-(0)49 376 3978
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PI: |
YES |
Taxa Studied: |
Invertebrate Animals |
Techniques Employed: |
Degenerate PCR, Quantitative PCR (qPCR), Sanger Sequencing, Solexa (Illumina) Sequencing, Bioinformatics/Sequence Analysis, In Situ Hybridization, Antibody Staining, Sectioning for Histology, Epifluoresence Microscopy, Confocal Microscopy, Time-Lapse Microscopy, Transgenesis, RNA interference(RNAi), Morpholinos |
Research Description: |
My research interests are focused in the mechanisms of regeneration and asexual development in ??basal? chordates. Colonial ascidians such Botryllus schlosseri are the closest relatives to vertebrates that, beside embryogenesis, can adopt two more distinct developmental pathways to regenerate their entire body, including all somatic tissues and the germline. My research aims are: (A) to understand the source of this regenerative plasticity, focusing on the molecules, cells and tissues involved in the two budding processes and, (B) to understand patterning and axis formation during regeneration at the molecular and morphological levels, and compare the mechanisms involved with those of embryogenesis. |
Lab Web Page: |
http://biodev.obs-vlfr.fr/ |
Willing to Host Undergraduates: |
YES |
Actively Seeking Undergraduates: |
YES |
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