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lab profile
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Igor Schneider Universidade Federal do Para
Rua Augusto Correa, 01
Belem, PA 66075-110
Brazil
ischneider.evodevo@gmail.com
55-91-80531100
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| PI: |
YES |
| Taxa Studied: |
Vertebrate Animals |
| Techniques Employed: |
Degenerate PCR, Quantitative PCR (qPCR), Solexa (Illumina) Sequencing, In Situ Hybridization, Antibody Staining, Sectioning for Histology, Scanning Electron Microscopy, Transgenesis |
| Research Description: |
What are the genetic underpinnings of morphological adaptations that led to terrestrial colonization by tetrapods? My lab uses the South American lungfish (Lepidosiren paradoxa) to study the genetic and developmental processes related to the transition from water to land. To achieve this, we utilize comparative genomic approaches with gene sets from the coelacanth, lungfish, ray-finned fishes and tetrapods, in order to evaluate gene gain and loss during the transition to the land environment. In addition we’re developing in vitro fertilization protocols to obtain developing lungfish eggs, to address evo-devo questions regarding fin to limb transition, evolution of heart chambers and the origin of the tetrapod lung. Finally, lungfishes possess a remarkable capacity for regenerating the fin endoskeleton, seldom observed in other fishes and typical of salamanders. We are studying lungfish fin regeneration to help establish the conserved and derived signaling pathways associated with appendage regeneration in vertebrates. |
| Lab Web Page: |
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| Willing to Host Undergraduates: |
YES |
| Actively Seeking Undergraduates: |
NO |
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